The clinical utility of Adenosine Deaminase (ADA) levels for the differentiation of tubercular and non-tubercular pleural effusion
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Date
2019-03
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Medical Sciences, Banaras Hindu University
Abstract
Background: Extra pulmonary TB accounts for 15% of all TB cases. Its incidence is much higher about 50% in HIV positive patients. Tuberculous pleurisy is present in around 4% of all TB cases2. Tuberculosis is always the leading etiology of pleural effusions in the developing countries3. Aims and Objectives: We have lot of investigations to diagnose pulmonary tuberculosis like sputum AFB, CBNAAT, LPA. These tests have some limitations in pleural fluid. So we are in need of a better test for diagnosis of tuberculous pleural effusion especially in high burden countries like India. Methods: In this study we have evaluated the usefulness of ADA level in pleural fluid for diagnosis of tuberculous pleural effusion. This study conducted from May 2017 to June 2018. Conclusion: This is a case control study done in a tertiary care center in Varanasi included 100 cases (Tuberculous pleural effusion) and 100 controls (Non Tuberculous pleural effusion).
Description
Keywords
Tuberculosis, Adenosine Deaminase, Pleural effusion
Citation
Rajak Bhupendra Kumar, Gupta Munesh Kumar, Mishra J.K., Thiru Anbarasan. The clinical utility of Adenosine Deaminase (ADA) levels for the differentiation of tubercular and non-tubercular pleural effusion. Indian Journal of Preventive & Social Medicine. 2019 Mar; 50(1): 12-17