Changes in Electrocardiogram Following Percutaneous Coronary Intervention and its Prognostic Implications
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Date
2018-10
Journal Title
Journal ISSN
Volume Title
Publisher
Ibn Sina Academy of Medieval Medicine & Sciences
Abstract
Background: The elevation of troponin-T (Trop-t) and creatinine kinase myocardial isoform (Ckmb) and elevation of these markers lead to major adverse cardiac events (MACEs). The association between above-mentioned parameters along with electrocardiogram (ECG) changes can be suitable diagnostic tool for myocardial injury following percutaneous coronary intervention (PCI). The present study was attempted to know the association of the changes in surface ECG and cardiac biomarkers and MACEs following PCI with the outcome in follow up among patients in eastern India. Methods: In present study, 100 patients were randomly selected for coronary angioplasty between April2012 to March2013. All the cases were referred to catheterization laboratory for elective PCI for single vessel or multivessel in native coronary artery. The biomarkers such as trop-t and Ckmb and MACEs along with changes in ECG were estimated as per standard protocol.
Results: ECG changes were statistically significantly correlated with post procedure Trop-t elevation (p<0.001), Ckmb elevation (p<0.001) and MACEs (P<0.01 and p<0.001) in 6 months followed up. Conclusion: In conclusion, the present study showed significant relationship between MACEs during followed up and changed in surface ECG along with Trop-t and Ckmb elevation in the post-PCI period of six-month followed up in stable ischaemic heart disease.
Description
Keywords
Biochemical markers, Percutaneous coronary intervention, Risk of myocardial damage, Surface ECG
Citation
Acharyya Malay, Mondal Indrajit, Mukhopadhyay Dipankar. Changes in Electrocardiogram Following Percutaneous Coronary Intervention and its Prognostic Implications. International Archives of BioMedical and Clinical Research. 2018 Oct-Dec; 4(4): 26-29