Methotrexate Induced Stevens Johnson Syndrome: A Rare Case Report

Methotrexate (MTX) is a folic acid antagonist with cytotoxic and immunosuppressant activity andwith potent antirheumatic action. It is commonly a first choice Disease modifying antirheumatic drug (DMARD). There were some spurious reports of Adverse Drug Reaction (ADR) by this drug. Here we report a rare occurrence of Stevens-Johnson syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) after the use of Methotrexate. Naranjo score for this adverse drug event was six, thereby making it a probable ADR. Symptomatic management of the patient was done and the offending drug was withdrawn. We are presenting this case to highlight the serious adverse reactions possible from a routinely prescribeddrug

Keywords

Methotrexate, Stevens-Johnson syndrome, Rheumatoid arthritis, Adverse Drug Reaction

Citation

Arora Surabhi, Abidi Afroz, Fatima Fariha, Hasan Roohana, Rizvi Darakhshan, Thadani Anupriya. Methotrexate Induced Stevens Johnson Syndrome: A Rare Case Report. Era's Journal of Medical Research. 2019 Jan-Jun; 5(2): 194-196

URI

https://imsear.searo.who.int/handle/123456789/184015

Collections

Era's Journal of Medical Research

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