Incidence of First Trimester Miscarriage among Women Undergoing ICSI According to Origin of Sperm for Male Factor and Non-male Factor.
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Date
2014-10
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Abstract
Prior to the development of intracytoplasmic sperm injection (ICSI), azoospermic and severely oligospermic men had little
to no chance of having a biological child. In this study, ICSI outcome in 212 transfers with ejaculated spermatozoa and 44
transfers with surgically retrieved spermatozoa were evaluated. Material and methods: The 68 singleton gestations achieved
by ICSI were segregated according to underlying infertility etiology, with 54.41% having male factor and 45.59% having
female factor. None of the patients had coexisting infertility factor. Results: The miscarriage rate of all ICSI singleton
gestations during the first trimester was 19.12%. There were no significant differences in early pregnancy loss (EPL)
rate by infertility factor. Among patients undergoing ICSI because of male factor, there were no significant differences
in EPL using ejaculated or nonejaculated sperm. Regardless of etiology, women aged ≥35 years had significantly higher
EPL (36.36%). Conclusion: Our preliminary results demonstrate that first trimester miscarriage rates of ICSI gestations
are not affected by underlying infertility etiology but are affected by maternal age.
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Keywords
Intracytoplasmic sperm injection, infertility, miscarriage, pregnancy
Citation
Gahlot Alka, Swarankar M L, Soni Ravikant. Incidence of First Trimester Miscarriage among Women Undergoing ICSI According to Origin of Sperm for Male Factor and Non-male Factor. Indian Journal of Clinical Practice. 2014 Oct; 25(5): 455-459.