Comparative Clinical Evaluation of Submucosal and Intramuscular Dexamethasone In Reducing Post Operative Sequelae Following Impacted Mandibular Third Molar Surgery.
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Date
2016-11
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Abstract
Background and Objectives: To understand the benefi ts of dexamethasone and to compare the effect of submucosal versus
intramuscular administration of dexamethasone in reducing post operative sequelae following impacted mandibular third molar
surgery.
Materials and Methods: The study was conducted on 90 patients, who were divided into three groups of 30 each. The two
experimental groups were given dexamethasone 4 mg submucosally or intramuscularly(preoperatively), and the control group did
not receive any form of corticosteroid. Measurement of facial swelling, maximal interincisal distance were made pre operatively
and on the fi rst, third and seventh post operative day. Pain was evaluated from patients response to visual analogue scale (VAS)
and recording the number of rescue analgesic tablets taken at the end of seventh postoperative day.
Results: Both dexamethasone groups showed a signifi cant reduction in pain, swelling and trismus as compared with the control
group at all intervals. There was a statistically signifi cant reduction in magnitude of swelling in submucosal dexamethasone group
as compared to intramuscular dexamethasone group on the 1st post operative day, but there was no signifi cant difference among
two experimental groups at other times and their effects were comparable for all variables.
Conclusion: Dexamethasone 4 mg is an effective therapeutic strategy for reducing post operative sequelae following surgical
removal of impacted third molars and submucosal dexamethasone is an effective alternative to dexamethasone given systemically.
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Keywords
Third molar surgery, Corticosteroids, Submucosal dexamethasone
Citation
Quadri Abdulhaseeb, Imran Mohammad, Quadri Shireen. Comparative Clinical Evaluation of Submucosal and Intramuscular Dexamethasone In Reducing Post Operative Sequelae Following Impacted Mandibular Third Molar Surgery. IJSS Journal of Surgery 2016 Nov-Dec; 2(6): 84-87.