Pituitary carcinoid coexisting with systemic lupus erythematosus: A rare combination.
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Date
2016-07
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Abstract
Gastrointestinal carcinoids have occasionally been reported in
patients with autoimmune diseases. We report a middle-aged
woman who presented with episodic hypertension and a skin
rash. Initial evaluation led to the diagnosis of systemic lupus
erythematosus for which the patient was treated. Further
investigations revealed the presence of a carcinoid tumour in
the pituitary. Although gastrointestinal carcinoids associated
with autoimmune diseases have been seen occasionally, to our
knowledge, extragastric carcinoid coexisting with an autoimmune
disorder has never been reported before. A better
understanding of how inflammation induces cytological changes
leading to development of a carcinoid from a cellular and
molecular perspective could provide potential therapeutic
strategies for preventing these lesions.
Natl Med J India 2016;29:209–11
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Bhambhani Anupam, Dugar Manish, Rao Jyotsna, Prasad Ravikanti. Pituitary carcinoid coexisting with systemic lupus erythematosus: A rare combination. National Medical Journal of India. 2016 Jul-Aug; 29(4): 209-211.