Vaccines for fungal infections
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Date
2015-01
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Abstract
High morbidity and mortality caused by mycotic infections has
been a cause for concern. Trials for various vaccines against
fungal pathogens have not been approved by the US Food and
Drugs Administration because of the high cost of production
and lack of a single suitable candidate. Most fungal infections
require cell-mediated immunity for their clearance. This has
been the basis for the development of various vaccines. We
discuss the various trials of candidate vaccines, the protective
efficacy as well as their shortcomings. Recent research suggests
that a universal vaccine can be prepared which may be effective
against most fungal pathogens.
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Citation
Tiwari Urvashi , Das Shukla, Tandon Mukta, Ramachandran V.G. , Saha Rumpa . Vaccines for fungal infections. National Medical Journal of India. 2015 Jan-Feb; 28(1): 14-19.