Plasmacytic or lymphoplasmacytic infiltrate in lymph nodes: Diagnostic approach and differential considerations.
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Date
2016-10
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Abstract
Plasmacytosis is a common finding in lymph node biopsies and can be seen
in diverse circumstances ranging from reactive lymphadenopathy to malignant
lymphoma. Familiarity with various histopathologic features of the different entities
and awareness of their typical clinical and ancillary study findings are essential
for an accurate diagnosis. In this review, we present common and representative
nonneoplastic entities and lymphomas that have plasmacytic differentiation or
associated plasmacytosis. We focus on the histological classification with an
emphasis on the diagnostic approach and areas of diagnostic challenge.
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Keywords
Castleman disease, lymph node, lymphoplasmacytic lymphoma, mucosa‑associated lymphoid tissue lymphoma, marginal zone lymphoma, plasmacytosis, primary effusion lymphoma, Rosai–Dorgman disease, syphilis, toxoplasma
Citation
Xie Yi, Vallangeon Bethany, Liu Xin, Lagoo Anand S. Plasmacytic or lymphoplasmacytic infiltrate in lymph nodes: Diagnostic approach and differential considerations. Indian Journal of Pathology & Microbiology. 2016 Oct-Dec 59(4): 446-456.