Biopsy techniques for intraocular tumors.
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Date
2016-06
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Abstract
Biopsy involves the surgical removal of a tissue specimen for histopathologic evaluation. Most intraocular
tumors are reliably diagnosed based on the clinical evaluation or with noninvasive diagnostic techniques.
However, accurately diagnosing a small percentage of tumors can be challenging. A tissue biopsy is thus
needed to establish a definitive diagnosis and plan the requisite treatment. From fine‑needle aspiration
biopsy (FNAB) to surgical excision, all tissue collection techniques have been studied in the literature.
Each technique has its indications and limitations. FNAB has been reported to provide for 88–95% reliable
and safe ophthalmic tumor diagnosis and has gained popularity for prognostic purposes and providing
eye conserving treatment surgeries. The technique and instrumentation for biopsy vary depending upon
the tissue involved (retina, choroid, subretinal space, vitreous, and aqueous), suspected diagnosis, size,
location, associated retinal detachment, and clarity of the media. The cytopathologist confers a very
important role in diagnosis and their assistance plays a key role in managing and planning the treatment
for malignancies.
Description
Keywords
Biopsy, cytology, eye, histopathology, malignancy, tumor
Citation
Rishi Pukhraj, Dhami Abhinav, Biswas Jyotirmay. Biopsy techniques for intraocular tumors. Indian Journal of Ophthalmology. 2016 June; 64(6): 415-421.