Enzyme Therapy: Current Perspectives.
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Date
2016-01
Authors
UmaMaheswari, Thiyagamoorthy
Hemalatha, Thiagarajan
Sankaranarayanan, Palavesam
Puvanakrishnan, Rengarajulu
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Abstract
Enzymes control all metabolic processes in human system from simple digestion of food to highly complex immune response. Physiological reactions occuring in healthy individuals are disturbed when enzymes are deficient or absent. Enzymes are administered for normalizing biological function in certain pathologies. Initially, crude proteolytic enzymes were used for the treatment of gastrointestinal disorders. Recent advances have enabled enzyme therapy as a promising tool in the treatment of cardiovascular, oncological and hereditary diseases. Now, a spectrum of other diseases are also covered under enzyme therapy. But, the available information on the use of enzymes as therapeutic agents for different diseases is scanty. This review details the enzymes which have been used to treat various diseases/disorders.
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Keywords
Alginate lyase, Antioxidant enzymes, Asparaginase, Bromelain, Cardiovascular, Collagenase, DNAases, Gastrointestinal, Glutaminase, Hemocoagulase, Hyaluronidase, Lipases, Oncological, Pancreatic enzymes, RNAases, Serratiopeptidase, Streptokinase, Therapeutics, Tissue plasminogen activator, Urokinase
Citation
UmaMaheswari Thiyagamoorthy, Hemalatha Thiagarajan, Sankaranarayanan Palavesam, Puvanakrishnan Rengarajulu. Enzyme Therapy: Current Perspectives. Indian Journal of Experimental Biology. 2016 Jan; 54(1): 7-16.