Dental stem cells.
Loading...
Date
2014-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
While the regeneration of a lost tissue is known to mankind for several years, it
is only in the recent past that research on regenerative medicine/dentistry has
gained momentum and eluded the dramatic yet scientific advancements in the
field of molecular biology. The growing understanding of biological concepts in
the regeneration of oral/dental tissues coupled with experiments on stem cells
is likely to result in a paradigm shift in the therapeutic armamentarium of
dental and oral diseases culminating in an intense search for “biological
solutions to biological problems.” Stem cells have been successfully isolated
from variety of human tissues including orofacial tissues. Mesenchymal stem
cells (MSCs) are multipotent stem cells which differentiate into a variety of cell
types. The potential MSCs for tooth regeneration mainly include stem cells from
human exfoliated deciduous teeth (SHEDs), adult dental pulp stem cells (DPSCs),
stem cells from apical part of the papilla (SCAPs), stem cells from the dental
follicle (DFSCs), periodontal ligament stem cells (PDLSCs) and bone marrow
derived mesenchymal stem cells (BMSCs). This review article outlines the recent
progress in mesenchymal stem cells used in tooth regeneration.
Description
Keywords
Dental stem cells, tooth engineering
Citation
Vashisht N, Vashisht D. Dental stem cells. International Journal of Medical and Dental Sciences. 2014 Jan; 3(1): 376-381.