Acquired amegakaryocytic thrombocytopenic purpura - An underdiagnosed entity.

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Date
2015-07
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Abstract
Acquired Amegakaryocytic Thrombocytopenic Purpura (AATP) is a rare cause of thrombocytopenia presenting over a wide age group with symptoms of bleeding and bone marrow showing isolated absence of megakaryocytes in an otherwise normal marrow. Here, we report a case of AATP in a three year old female child who was then treated with anti thymocyte globulin successfully. We report this case because of it’s under diagnosis or misdiagnosis as immune thrombocytopenia (ITP) in most of the cases. We also review the literature regarding the pathogenesis and treatment of this undiagnosed entity.
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Keywords
Amegakaryocytic thrombocytopenia, misdiagnosis, anti thymocyte globulin, rare, bone marrow
Citation
Sindhu R, Behera SK, Nayak J, Mishra DP. Acquired amegakaryocytic thrombocytopenic purpura - An underdiagnosed entity. International Journal of Medical and Dental Sciences. 2015 July; 4(2): 897-900.