Comparative Study of Serum Lipid Profile in Normotensive Pregnant Women and in Patients with Pre-Eclampsia- A Case Control Study.
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Date
2016-03
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Abstract
Background: The objective of the present study was to compare the changes in serum lipid profile in normal pregnant
women with those in patients with pre-eclampsia. Methods: In this study total 140 study subjects were evaluated, 70
normotensive pregnant women as a control group and 70 pre-eclamptic patients as a study group. Study Subjects were
between the age group of 20-35 years and in the second and third trimester of pregnancy. Fasting blood samples were
collected and serum level of Triglycerides (TG), Total Cholesterol (TC), High Density Lipoprotein (HDL), Low Density
Lipoprotein (LDL), and Very Low Density Lipoprotein (VLDL) were measured by enzymatic colorimetric method.
Results: There was a significant rise in TC, TG, LDL and VLDL and significant decrease in HDL level in pre-eclamptic
group as compared to normal pregnant women.Conclusion: The findings of the present study are consistent with
previous studies suggesting an altered lipid profile has a potential role in the genesis of endothelial dysfunction and
expression of pre-eclampsia.
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Keywords
Pre-eclampsia, Lipid Profile, TG, HDL, LDL, VLDL
Citation
Gupta Ranjana, Gupta Tripti, Srivastava Sugandh, Premi H K, Saxena Shikha, Sharma Mahendra. Comparative Study of Serum Lipid Profile in Normotensive Pregnant Women and in Patients with Pre-Eclampsia- A Case Control Study. Annals of International Medical and Dental Research. 2016 Mar-Apr; 2(2): 108-111.