Seroprevalence of Transfusion Transmitted Infections in Healthy Blood Donors in Specific Class of Kuppuswamy’s Socio-Economic Status Scale.
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Date
2016-07
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Abstract
Background: Blood transfusion has profound role to play in specific illness, but still
due to unsafe and careless practices the peril of transfusion transmissible infections
(TTIs) such as human immunodeficiency virus (HIV), hepatitis C virus (HCV),
hepatitis B virus (HBV), syphilis and malaria prevails.
Objective: To study the seroprevalence of TTIs in healthy blood donors in specific
Kuppuswamy’s socio-economic scale at a Blood Bank of a tertiary care teaching
hospital in north India, to enhance the awareness about transfusion related risks and
to implement better strategic measures to prevent TTI, in high risk groups.
Material and Method: Total 10,569 blood units were collected from Jan-2014 to
Septmeber-2015. All donors were categorised according to the Kuppuswamy’s Socioeconomic
Status Scale (KSESS) followed by screening of all sera samples for hepatitis B
surface antigen (HBsAg), antibodies to HCV, HIV types 1 and 2 using enzyme-linked
immunosorbent assays (ELISA) and for malaria antigen and Treponema pallidum by using
immunochromatographic tests and Rapid Plasma Reagin test (RPR) respectively. All the
samples found reactive for HIV, HBsAg, and HCV were again confirmed by second ELISA.
Results: The overall seroprevalence was HCV 2.06 % (218/10569) > HBV 1.71%
(181/10569) > HIV 0.03% (3/10569). No donor was found positive for Malaria
and VDRL. The prevalence of transfusion transmissible diseases in specific socio
economic class was as follows-:Upper lower class (IV) 248/2261 (10.96%) > Lower
class (V) 34/483 (7.03%) > Lower Middle class (III) 97/5789 (1.67%) > Upper middle
class (II) 22/1552 (1.42%) > Upper class (I) 1/484 (0.20%) and seroprevalence of
transfusion transmissible diseases in each socio economic class, out of total donations
was as follows-: Upper lower class (IV) 248/10569 (2.35%)> Lower middle class
(III) 97/10569 (0.92%) >Lower class (V) 34/10569 (0.32%)> upper middle class (II)
22/10569 (0.21) >Upper class (I) 1/10569 (0.009%).
Conclusion: Maximum positive TTIs had association with low socio-economic status
people with increased medical and behavioral risk factors. Hence, we conclude that
awareness among the high risk population group, strict and skillfulness selection of donors
and use of effective laboratory screening tests is the prerequisite for the safe donation!!
Description
Keywords
Enzyme-linked immunosorbent assays, Kuppuswamy’s Socio-Economic Status Scale, Transfusion Transmitted Infections
Citation
Khattri Jyotsana, Awasthi Seema, Ahmed Faiyaz, Kumar Ashutosh, Dutta Shyamoli, Vyas Priti, Mittal Ankita. Seroprevalence of Transfusion Transmitted Infections in Healthy Blood Donors in Specific Class of Kuppuswamy’s Socio-Economic Status Scale. Acta Medica International. 2016 Jul-Dec; 3(2): 9-14.