Narrative Review: Genetic Findings in Patients of Generalized Anxiety Disorder.
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Date
2015-07
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Abstract
General anxiety disorder is a chronic disorder. The prevalence of GAD is variable in different part of world, with some region having
higher figure than others. It’s uncertain to quote if the variation is due to genetic loading or environmental factors. It is twice more
common in females than males. It has constituted substantial burden on global economy as well as over all quality of life of an
individual suffering from GAD. The prognosis of GAD is mainly correlated with the environmental constraints. However, the efficacy
of response to pharmacological intervention is better explained on biological model. Certain studies are done to widen the ground
of genesis of GAD. Although, by and large it still remains debatable about distinctive gene causing GAD. Nonetheless, the alteration
of gene coding of 5-HTTLPR of serotonin is relatively favorable finding in studies, both independently done on GAD and in parallel
to other anxiety disorders and psychiatric morbidities.
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Keywords
Generalized Anxiety Disorder, genetics, neurobiology
Citation
Abbas Aamir, Channa Afshan. Narrative Review: Genetic Findings in Patients of Generalized Anxiety Disorder. Acta Medica International. 2015 July-Dec; 2(2): 143-148.