Dermatonecrotic lesions in rabbits caused by neuraminidase.

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Date
1992-05-01
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Abstract
In an attempt to study the role of neuraminidase in cholera vibrio pathogenesis, the dermatonecrotic effect of a purified neuraminidase preparation was studied in rabbits. The experiments demonstrated that dermatonecrotic lesions resulted from intracutaneous injection of a purified neuraminidase preparation (0.5 specific human dose or 1 NU) as well as significant doses of cholera toxoid containing the enzyme (4,12,18 specific human doses).
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Isupov IV, Sagheyeva OF, Yeliseyev YuYu , Adamov AK, Sayapina LV, Kovalenko NM, Lukyanova OI. Dermatonecrotic lesions in rabbits caused by neuraminidase. Indian Journal of Medical Research. 1992 May; 95(): 152-6
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https://imsear.searo.who.int/handle/123456789/17661
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Indian Journal of Medical Research