Hepatoid Carcinoma of Adrenal Gland: A Case Report.
Loading...
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Aims: Hepatoid carcinoma is a rare tumor that mimics the morphologic and immunohistochemical
features of hepatocellular carcinoma. An exceptional occurrence in adrenal gland has been
recorded in the literature. The aim of this work is to study the morphologic immunohistochemical
differential diagnosis and prognosis of adrenal hepatoid carcinoma.
Presentation of Case: We present a rare case of hepatoid carcinoma of left adrenal gland in 70-
year-old-men. Histologically, the adrenal mass was composed of cells with enlarged nuclei,
proeminent nucleoli and eosinophilic cytoplasm, arranged in a pseudoglandular and thick
trabecular pattern with bile plugs, which resembled hepatocellular carcinoma. The main differential
diagnosis was adrenal metastasis from hepatocellular carcinoma. The adrenal gland origin of the
hepatoid carcinoma was verified by the absence of liver mass on clinical and imagery grounds.
Conclusion: We present the first case of adrenal hepatoid carcinoma in Tunisia. The main
differential diagnosis was adrenal metastasis from hepatocellular carcinoma, which was eliminated
by the absence of liver tumor.
Description
Keywords
Hepatoid, adenocarcinoma, adrenal gland, histopathology, liver, hepatocellular carcinoma
Citation
Gouiaa Naourez, Mellouli Manel1, Abid Najla, Kallel Rim, Bahri Ibticem, Kharrat Maha, Ammar Jamel, Boudawara Tahiya. Hepatoid Carcinoma of Adrenal Gland: A Case Report. British Journal of Medicine and Medical Research. 2015; 5(12): 1590-1594.