BisGMA and TEGDMA Elution from Two Flowable Nanohybrid Resin Composites: An In vitro Study.
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Date
2015
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Abstract
Aim: The aim of our study was to evaluate the amount of release of BisGMA and TEGDMA from
two commercially available enamel replacement composites; Tetric N-Flow™ and G-aenial
Universal Flo™ over a period of 24 hours after polymerization with a standard LED Curing Unit.
Methods and Materials: Two flowable nanohybrid composite materials; Tetric N-Flow™ (Ivoclar
Vivadent AG, Liechtenstein) and G-aenial Universal Flo™ (GC, India) were investigated and
grouped into two groups. Ten samples from each group were prepared by inserting the material
into a standardized Teflon mould of size 2x2x2 mm. Each sample was cured with a LED curing unit
for 20 seconds and was stored in 2 ml of Ethanol at room temperature. After 24 hours, the samples
were removed from the storage medium (ethanol) and prepared for measurements. A reverse
phase HPLC unit was used to detect the release of BisGMA and TEGDMA monomers from the
prepared samples. The acquired measurements were obtained after testing them in a High Liquid
Performance Chromatography Unit. The data obtained was statistically analyzed and the results
revealed significant amount of release of TEGDMA as well as BisGMA Results: G-aenial Universal Flo™ showed significant release of both TEGDMA as well as BisGMA
as compared to Tetric N- Flow™. The increase was by 0.5 units.
Conclusion: Significant amount of release of TEGDMA as well as BisGMA was seen in both the
composite materials after HPLC Unit analysis. This can help in the evaluation of cytoxicity to the
soft tissues in the oral environment.
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Keywords
BisGMA, flowable composites, HPLC unit, monomer elution, TEGDMA
Citation
Hegde Mithra N, Wali Ankita. BisGMA and TEGDMA Elution from Two Flowable Nanohybrid Resin Composites: An In vitro Study. British Journal of Medicine and Medical Research. 2015; 5(9): 1096-1104.