Electrocardiographic and Echocardiographic Evaluation of Heart in Newly Diagnosed Hypothyroid Patients.
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Date
2016-01
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Abstract
Background: Hypothyroidism is a clinical syndrome resulting from a deficiency of thyroid hormones, which in turn
results in a generalized slowing down of metabolic processes. Hypothyroidism affects 2% of adult women and 0.1-0.2%
of adult men. Thyroid hormones exert direct cellular effects on almost all tissues of the body. It causes multi-organ
dysfunction due to deranged metabolism. Objectives: To study Electrocardiographic and echocardiographic evaluation
of heart in newly diagnosed hypothyroid patients. Methods: This study was a conducted as a prospective study carried
out from January 2012 to July 2013 at Mediciti Institute of Medical Sciences. The criteria for diagnosis of hypothyroidism
was Clinical assessment, Thyroid hormone assay–TSH - >5 μIU/ml, FT4 - < 0.7 ng/dl, FT3 - < 2.4 pg/dl. Investigations
like Complete Blood Picture, Complete Urine Examination, Random Blood Sugar, Blood urea, Serum Creatinine,
Fasting lipid profile, Chest X Ray, Standard 12 Lead ECG were done. Results: On systemic examination, Cardiomegaly
and diminished heart sound was found in 13.3% and 9.99% patients. Normal ECG is found in 36.66% of patients before
treatment and 66.66 % after treatment. Bradycardia is most common finding seen in 6 patients counting for 20%,
followed by low voltage complexes and ST changes in 16.66% patients respectively before treatment. Echo findings are
normal in 43.33% cases before treatment and 66.66% after treatment. Pericardial effusion and Diastolic dysfunction are
the common findings seen in 8 cases each accounting to 26.66% cases, which reduced to 13.3% and 9.99%
respectively after management. Systolic dysfunction was found in 9.99% of patients after treatment. Conclusion:
Hypothyroid state, which has significant impact on cardiac structure/function associated with increased CVS morbidity
and mortality is reversible with treatment.
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Keywords
Hypothyroid state, cardiac structure, morbidity, mortality
Citation
Anusha K, Kumar Ravindra. Electrocardiographic and Echocardiographic Evaluation of Heart in Newly Diagnosed Hypothyroid Patients. Annals of International Medical and Dental Research. 2016 Jan-Feb; 2(1): 377-380.