Use of DonnatalTM Elixir in the Treatment of Neonatal Abstinence syndrome.
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Date
2014-12-01
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Abstract
We present the case of a 6-week-old male infant with Neonatal Abstinence Syndrome
(NAS) in which DonnatalTM (phenobarbital, hyoscyamine, atropine, hyoscine) Elixir was
used as an adjunct therapy. The infant was born to a mother taking 130mg of methadone
per day since conception. Due to NAS, he was treated with a methadone taper and oral
clonidine. Yet, despite the majority of symptoms being suppressed with these
medications, he remained stricken with colicky pain, unresponsive to supplemental
opioids. A trial of DonnatalTM resulted in relief of symptoms and completion of his opioid
taper. We recommend DonnatalTM as part of the treatment plan for refractory abdominal
symptoms in cases of NAS.
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Keywords
DonnatalTM;, belladonna alkaloids, withdrawal, colic, neonatal abstinence syndrome, visceral abdominal pain
Citation
Brzenski Alyssa ,Greenberg Mark. Use of DonnatalTM Elixir in the Treatment of Neonatal Abstinence syndrome. British Journal of Medicine and Medical Research. 2014 Dec; 4(34): 5446-5450.