High Anion Gap Metabolic Acidosis among Children with Nodding Syndrome (NS) in Northern Uganda: Case Series.
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Date
2014-02-21
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Abstract
Aims: To conduct a hormonal and biochemical studies on 10 patients with diagnosis of
probable Nodding Syndrome (NS).
Study Design: A cross-sectional study
Place and Duration of Study: Atanga Health Center III in Pader District in Northern
Uganda in September 2012.
Methodology: We recruited consecutively 10 children with probable Nodding Syndrome
who had been admitted for symptomatic management of seizures, injuries resulting from
falls and nutritional rehabilitation. History, physical examinations, biophysical
measurements (anthropometry) and blood investigations including serum electrolytes,
liver function tests, thyroid hormones and vitamin D assays. Ethical approval was
obtained from Gulu University Institutional Review Committee.
Results: All children had severely low serum calcium and bicarbonate levels and a high
Anion Gap. Thyroid hormones and vitamin D assays were largely normal.
Conclusion: Children with Nodding Syndrome undergoing treatment for seizure control
and nutritional rehabilitation have high Anion Gap metabolic acidosis.
Description
Keywords
Nodding Syndrome, metabolic acidosis, high Anion Gap, hormones, Pader, Northern Uganda
Citation
Kitara David Lagoro, Mwaka Amos Deogratious, Kigonya Edward. High Anion Gap Metabolic Acidosis among Children with Nodding Syndrome (NS) in Northern Uganda: Case Series. British Journal of Medicine and Medical Research. 2014 Feb; 4(6): 1301-1314.