Coagglutination for rapid testing of toxin producing Corynebacterium diphtheriae.

No Thumbnail Available
Date
1993-01-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Coagglutination test was standardised for rapid detection of diphtheria toxin after primary culture of C. diphtheriae isolates on conventional Loeffler's medium. The procedure was optimised with diphtheria toxoid (DT)-antidiphtheritic serum (ADS) system wherein Cowan-I strain of Staphylococcus aureus was sensitised with ADS. Toxoid in the range of 1.02 lf/ml to 4200 lf/ml could be detected by the present procedure. Toxin of C. diphtheriae could be demonstrated in five of eight clinical isolates, this correlated with the conventional guinea pig pathogenicity test. The coagglutination test thus needs further confirmation of its potential as a simple and satisfactory test for rapid detection of toxin-producing C. diphtheriae.
Description
Keywords
Citation
Jalgaonkar SV, Saoji AM. Coagglutination for rapid testing of toxin producing Corynebacterium diphtheriae. Indian Journal of Medical Research. 1993 Jan; 97(): 35-6
URI
https://imsear.searo.who.int/handle/123456789/17475
Collections
Indian Journal of Medical Research