Study of Trophoblasts and Histological Changes of Fallopian Tube in Tubal Pregnancy and Anatomical Considerations for Its Early Rupture.
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Date
2014-10
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Abstract
Fertilisation takes place in the lumen of fallopian tube, from where, aided by the ciliated columnar epithelium
of the tube, the fertilised ovum makes its way into uterine cavity and the implantation occurs. The passage of
fertilised ovum into uterine cavity is delayed or obstructed by developmental, mechanical or other defects
which lead to tubal gestation. The incidence varies from 1 in 300 to 1 in 150 pregnancies and it contributes
significantly to the maternal mortality and morbidity. Early diagnosis and therapy has helped to reduce the
maternal death due to ectopic pregnancy. However, study on histological changes of early ectopic pregnancy
are rather scarce and therefore, the present study was conducted on 25 patients of ectopic pregnancy specimens
observed for the mode and extent of invasion of chorionic villi, and the histological changes in wall of the
fallopian tubes to evaluate the causes of early tubal rupture as well as estimation of gestational age by the
study of chorionic villi.
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Keywords
Fallopian tube, Chorionic villi, Ectopic pregnancy, Tubal rupture, Nidation
Citation
Sowmya S, Priya R, Meenakshi P, Shwetha B. Study of Trophoblasts and Histological Changes of Fallopian Tube in Tubal Pregnancy and Anatomical Considerations for Its Early Rupture. International Journal of Anatomy and Research. 2014 Oct-Dec; 2(4): 609-613.