Tuberculous intestinal perforation in a case of Burkitt lymphoma on chemotherapy - A case report.
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Date
2015-07
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Abstract
Intestinal perforation induced by chemotherapy in a patient of Burkitt lymphoma is a known potential complication which
carries high mortality. Perforation may also occur as a result of the transmural nature of the tumour. Patients on chemotherapy
are prone to contract infectious diseases due to a compromised immune system. Pulmonary tuberculosis has been reported in
these patients, but abdominal tuberculosis has not. We report the case of a five year old boy on chemotherapy for Burkitt
lymphoma, and who developed a tuberculous jejunal perforation. The patient underwent drain insertion and stabilization
followed by exploratory laparotomy with resection of the pathological segment and closure of the duodenal stump at the fourth
part. Bowel continuity was re-established by gastrojejunostomy. Histopathologic examination of the resected segment revealed
intestinal tuberculosis. Anti -tubercular therapy was started and continued for nine months. The last cycle of chemotherapy was
administered 1 month after surgery. At 1 year of follow up the patient is asymptomatic and thriving well.
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Keywords
Burkitt lymphoma, Bowel Perforation, Intestinal Tuberculosis
Citation
Kekre Geeta, Gupta Rahul, Gupta Abhaya, Kothari Paras, Patil Prashant, Dikshit Vishesh, Kamble Ravi. Tuberculous intestinal perforation in a case of Burkitt lymphoma on chemotherapy - A case report.Indian Journal of Case Reports. 2015 July-Dec; 1(3&4): 61-64.