Disseminated Histoplasmosis in a Patient with Advanced HIV Disease—Lessons Learnt from Bangladesh.
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Date
2010-06
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Abstract
Histoplasmosis is a systemic fungal disease, also known as Darling’s disease, caused by the dimorphic fungus
Histoplasma capsulatum. It is usually self-limiting or localized in immunecompetent individuals whereas
in patients with acquired immune deficiency syndrome (AIDS), it occurs in the disseminated form in 95%
of cases. Although histoplasmosis predominates in the Americas (United States and Latin America, including
Brazil) as an important infection among AIDS patients, it is not common in Bangladesh. In contrast,
tuberculosis is extremely common in Bangladesh, with an estimated prevalence of 387 per 100,000 people.
Here, a confirmed case of disseminated histoplasmosis is reported in Bangladesh in a known HIV-positive
patient, which was initially suspected to be extrapulmonary tuberculosis.
Description
Keywords
Case studies, Histoplasma capsulatum, Histoplasmosis, HIV, Tuberculosis, Bangladesh
Citation
Pervez Md. Moshtaq, Cobb Brian, Matin Nashaba, Shahrin Lubaba, Ford Evelyn R, Pietroni Mark. Disseminated Histoplasmosis in a Patient with Advanced HIV Disease—Lessons Learnt from Bangladesh. Journal of Health, Population and Nutrition. 2010 Jun; 28(3):305-307.