Protective effect of Lannea coromandelica Houtt. Merrill. against three common pathogens.
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Date
2013-10
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Abstract
Background: Ayurvedic text reports suggested Lannea coromandelica is used in various microbial origin disorders like
dysentery, sore eyes and leprosy, genital wounds. Objective: The present study was designed to investigate the antimicrobial
effect of L. coromandelica Houtt. Merrill. (Anacardiaceae) on microbes which cause female reproductive tract infection.
Materials and Methods: Ethanolic and aqueous bark extract (Ext.) of L. coromandelica were screened against strains of
Streptococcus pyogens, Staphylococcus aureus, and Candida albicans. Antimicrobial assay had been done with agar well
diffusion method. Results: Ethanolic extracts [100% (16 mg), 75% (12 mg) and 50% (8 mg)] of L. coromandelica exhibited
zone of inhibition (ZI) 19.21 mm, 18.45 mm, 16.41 mm and 18.12 mm, 17.35 mm, 16.35 mm against S. aureus and
S. pyogens, respectively. However, only 100% and 75% ethanolic extract showed (ZI-19.18 mm, 16.29 mm) activity
against C. albicans. Nevertheless, aqueous extract (100%) showed higher antifungal activity (ZI-16.97 mm). Ciprofl oxacin
and amphotericin B were used as a standard drugs in the present study. Conclusion: The results demonstrated that
L. coromandelica Houtt. Merrill. have antibacterial activity against S. pyogens, S. aureus and antifungal property against
C. albicans. Our fi ndings corroborate the ethnobotanical use of L. coromandelica in traditional medicine system (Ayurveda)
of India.
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Keywords
Agar well diffusion method, antibacterial, antifungal, ayurveda, Candida albicans, female reproductive tract infection, Lannea coromandelica, Staphylococcus aureus, Streptococcus pyogens
Citation
Kaur Rupinder, Jaiswal Mohan Lal, Jain Vivek. Protective effect of Lannea coromandelica Houtt. Merrill. against three common pathogens. Journal of Ayurveda and Integrative Medicine. 2013 Oct-Dec; 4(4): 224-228.