Association of Streptococcus with Plaque Type of Psoriasis.
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Date
2015-05
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Abstract
Background: Guttate psoriasis has a well-known association with streptococcal throat infections,
but the effects of these infections in patients with chronic plaque type of psoriasis remains to be
evaluated. In Bangladesh several studies were done on psoriasis but no data about association
between streptococcal throat infection and plaque type psoriasis are available so far. Considering
the co-morbidities of psoriasis patients, it might be justifiable to find out the events that provoke
the initiation or exacerbation of psoriatic disease process. Objective: To observe the association of
streptococcus with plaque type of psoriasis. Materials and Methods: This observational study was
conducted in the department of Dermatology and Venereology, Bangabandhu Sheikh Mujib
Medical University, Dhaka. Forty seven patients clinically and histopathologically diagnosed as
having plaque psoriasis were selected as cases and patients with skin diseases other than psoriasis
were selected as controls. Results: In this study majority of subjects (55%) were diagnosed as
chronic plaque psoriasis. Among the subjects with guttate flare of chronic plaque psoriasis 64.2%
gave a positive history of sore throat. ASO titer was raised (>200 IU/mL) in 28 (59.5%) patients of
chronic plaque psoriasis and 7 (17.9%) patients of non-psoriatic respondents. The difference
between two groups was significant (p<0.05). Streptococcus pyogenes was found in 12 (25.5%) in
chronic plaque psoriasis patients versus in 4 (10.2%) in controls (p>0.05). Conclusion: This study
shows that streptococcal throat infections are associated with plaque psoriasis and early treatment
of throat infections may be beneficial for plaque type of psoriasis patients.
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Keywords
Streptococcal throat infections, Chronic plaque psoriasis, Guttate flare of chronic plaque psoriasis
Citation
Hossain Mohammad Akram, Khondker Lubna. Association of Streptococcus with Plaque Type of Psoriasis. Journal of Enam Medical College. 2015 May; 5(2): 99-103.