Diabetic Ketoacidosis: Pattern of Precipitating Causes 1. Medical.
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Date
2014-05
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Abstract
Background: Diabetic ketoacidosis (DKA) is one of the most common acute complications of
diabetes mellitus (DM). DKA is a recognised presenting feature of type 1 DM, but it
commonly complicates previously diagnosed diabetic patients of all types, specially if they get
infection or discontinue treatment. Objective: To describe the precipitating causes of DKA.
Materials and Methods: This cross-sectional study was done from September to November,
2010 in Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine and
Metabolic Disorders (BIRDEM). Diagnosed DKA cases were evaluated clinically and by
laboratory investigations for identification of precipitating causes. Results: Out of 50
patients, 28 were female. Mean age was 38.3 years. Forty patients (80%) were known
diabetics and 10 (20%) were detected diabetic first time during this admission. Severe DKA
cases were less common. Infection (20, 40%) was the commonest precipitating cause followed
by noncompliance (14, 28%). In 7 (14%) cases no cause could be identified. Other less
common causes included acute myocardial infarction, acute pancreatitis, stroke and surgery.
Conclusion: Infection and noncompliance were the major precipitants of DKA. So, it is
assumed that many DKA cases might be prevented by proper counselling regarding adherence
to medication and sick days’ management.
Description
Keywords
Diabetes mellitus, Diabetic ketoacidosis, Precipitating causes, Risk factors
Citation
Ahmed Ashraf Uddin, Rahim Muhammad Abdur, Rahman Md Raziur, Nazim Reshad Falah, Uddin Khwaja Nazim. Diabetic Ketoacidosis: Pattern of Precipitating Causes 1. Medical. Journal of Enam Medical College. 2014 May; 4(2): 94-97.