Bacterial Isolates and their Antibiotic Sensitivity Pattern in Clinically Suspected Cases of Fever of Unknown Origin.
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Date
2014-07
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Abstract
The present study was conducted on 100 suspected cases of fever of unknown origin to identify the
prevalence of predominant bacterial microorganisms and their drug sensitivity pattern. The blood samples
were subjected to conventional blood culture and BACTEC 9050 culture system. Out of 100 suspected
cases, culture positivity was seen in 46% cases with 80.43% pathogenic bacterial isolates comprising of
54.05% gram positive and 45.94% gram negative isolates. Predominant gram positive isolates were
coagulase negative Staphylococcus 35% followed by 30% Staphylococcus aureus with sensitivity to
vancomycin (100%) and resistance to ampicillin, cloxacillin & cefalexin. Gram negative isolates were
Salmonella typhi (29.41%) followed by E coli (17.64%) showing sensitivity to piperacillin/tazobactum and
cefoperazone/sulbactum (90%) each and resistance to amoxicillin. BACTEC 9050 was observed to be
sensitive(100%) as compared to conventional blood culture(67.56%) for cultural isolation of pathogenic
organisms in clinical specimens.
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Keywords
BACTEC 9050- Becton Dickinson Microbiology Systems, Fever of Unknown Origin
Citation
Kaur Avneet, Singh Varsha A. Bacterial Isolates and their Antibiotic Sensitivity Pattern in Clinically Suspected Cases of Fever of Unknown Origin. JK Science Journal of Medical Education and Research. 2014 Jul-Sept; 16(3): 105-109.