Ewing's Sarcoma of the Rhinomaxillary Complex: A case Report with Review of Literature.
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Date
2013-01
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Abstract
Ewing's Sarcoma of bone (ESB) is a rare primary malignant tumor of bone, belonging to Ewing's Sarcoma
Family of Tumors (EFT) and are neuro-ectodermal in origin. These tumors are characterized
histopathologically as small round blue cell tumors (SRBCT) containing cytoplasmic glycogen, cytogenetically
by a (t:11;22) or (q:24;12) translocation and molecularly by the presence of EWS and FLI1 fusion transcripts.
ESB is primarily a pediatric tumor, uncommon in the Asian population, affecting the axial skeleton and
rarely the jaw bones. ESB poses a diagnostic challenge as it shares many features with other malignant
tumors whose managements are substantially different. We present the clinical, radiographic histopathological
and immuno histochemical features of ESB involving the left rhinomaxillary complex in a young Indian
male. We also discuss the differential diagnosis and current treatment modalities in management of ESB.
Description
Keywords
Ewing's Sarcoma of Bone, Rhinomaxillary Complex, Small Round Blue Cell Tumors
Citation
Gupta Shalini R, Singh Inderpreet, Saran R K, Kumar Priya. Ewing's Sarcoma of the Rhinomaxillary Complex: A case Report with Review of Literature. JK Science Journal of Medical Education and Research. 2013 Jan-Mar;15(1): 38-40.