Pulse Oximetry Screening to Detect Cyanotic Congenital Heart Disease in Sick Neonates in a Neonatal Intensive Care Unit.
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Date
2015-09
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Abstract
Objective: To evaluate pulse oximetry for detection of congenital cyanotic heart disease in
sick neonates using echocardiography as gold standard.
Methods: Pulse oximetry readings were taken at admission from 950 neonates from right
upper limb and either foot with infant breathing room air. Pulse oximetry was considered
abnormal if oxygen saturation at room air measured <90% or difference between right hand
and foot was more than 3%. Persistent abnormality was considered positive result.
Echocardiography was performed on all neonates with positive pulse oximetry (study
group) and on one subsequent neonate with negative screen for each neonate with positive
screen (controls).
Results: Pulse oximetry was positive in 210 neonates. It detected 20 out of 21 (95.2%) true
positives. The sensitivity, specificity, positive predictive value, negative predictive value and
odds ratio (95% CI) of pulse oximetry was 95.2%, 52.4 %, 9.5, 99.5 and 22 (5.3, 91.4),
respectively.
Conclusion: Pulse oximetry screening is useful in detecting cyanotic heart diseases in sick
newborns.
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Keywords
Cyanosis, Duct-dependent lesions, Oxygen saturation, Screening
Citation
Mathur N B, Gupta A, Kurien S. Pulse Oximetry Screening to Detect Cyanotic Congenital Heart Disease in Sick Neonates in a Neonatal Intensive Care Unit. Indian Pediatrics. 2015 Sept; 52(9): 769-772.