Trans-Septal Trans-Sphenoidal Surgery For Pituitary Adenomas:A Retrospective Study.
Loading...
Date
2010-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In this retrospective study 100 patients of pituitary adenoma who underwent Trans-septal Trans-sphenoidal
surgery over 10 years period were evaluated. The mean presenting complaints of these patients were
headache and decreased vision. Majority of tumors in our study were non functioning adenomas (39%)
followed by prolactinomas (38%), growth hormone producing tumors constituted 20%, where as cortisol
secreting adenomas were 3%. There was no operative mortality in our series. Post-op CSF rhinnorrhoea
was noted in 3 patients - out of these one patient required surgical repair of fistula in immediate postoprated
period while other two patients were managed with lumbar drain. Total excision of tumor was
attained in 38% of patients as these were evaluated by post-oprated CT scan and MRI with contrast.
30% of patients were given radiotherapy immediately after the surgery. These were patients in whom
residual tumor was more than 1 cm in size and the hormone levels did not return to normal. The patients
were followed up from 9 months to 10 years with a mean follow up of 4 years. There were total of 18
recurrences on follow up study.
Description
Keywords
Pituitary adenoma, Transsphenoidal Excision
Citation
Sabharwal Sudhir, Palande D A, Velho Vernon. Trans-Septal Trans-Sphenoidal Surgery For Pituitary Adenomas:A Retrospective Study. JK Science Journal of Medical Education and Research. 2010 July-Sept; 12(3): 123-126