Childhood Hepatosplenic T-cell Lymphoma with Skin Involvement.
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Date
2015-05
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Abstract
Background: Hepatosplenic T-cell lymphoma is a rare malignancy in childhood. Case
characteristics: A 12-year-old boy who presented a pyrexia of unknown origin, multiple skin
and lesions and marked hepatosplenomegaly. Observation: Bone marrow aspirate
cytology showed no blast cells. Splenectomy was done, and spleen showed infiltration with
atypical lymphoid cells positive for CD3, CD8 and T-cell-restricted intracellular antigen.
Outcome: The skin rash of patient subsided with chemotherapy. Message: Skin
involvement may be an unusual clinical manifestation of hepatosplenic T-cell lymphoma.
Description
Keywords
Diagnosis, Non-Hodgkin lymphoma, Splenectomy
Citation
Guo Xia, Li Qiang, Zhu Yi-Ping. Childhood Hepatosplenic T-cell Lymphoma with Skin Involvement. Indian Pediatrics. 2015 May; 52(5): 427-428.