Nasal Intermittent Positive Pressure Ventilation with Heliox in Premature Infants with Respiratory Distress Syndrome: A Randomized Controlled Trial.
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Date
2014-11
Journal Title
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Abstract
Objective: To assess the efficacy of nasal intermittent positive pressure ventilation with
heliox in preterm infants with respiratory distress syndrome.
Methods: Premature infants with mild respiratory distress syndrome requiring non-invasive
respiratory support were eligible. Infants were randomly assigned to heliox or air-oxygen
group. The main outcome was the length of ventilation.
Results: Heliox significantly decreased the length of ventilation. The length of ventilation was
positively correlated with interleukin-6 at baseline. Carbon dioxide elimination was better in
the heliox group.
Conclusion: Heliox delivered with nasal intermittent positive pressure ventilation may be
effective in reducing length of ventilation and increasing carbon dioxide elimination.
Description
Keywords
Helium, Oxygen, Prematurity, Ventilation
Citation
Li Xue, Shen Jie, Zhao Jinlin, Tang Shifang, Shi Yuan. Nasal Intermittent Positive Pressure Ventilation with Heliox in Premature Infants with Respiratory Distress Syndrome: A Randomized Controlled Trial. Indian Pediatrics. 2014 Nov; 51(11): 900-902.