Trier Social Stress Test in Indian Adolescents.
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Date
2014-06
Journal Title
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Abstract
Objective: To test the Trier Social Stress Test for children (TSSTC)
in a cohort of Indian adolescents.
Design: Cohort study
Setting: Holdsworth Memorial Hospital, Mysore, India.
Participants: Adolescent children (N=273, 134 males; mean age
13.6 yrs) selected from an ongoing birth cohort; 269 completed
the test.
Intervention: Performance of 5-minutes each of public- speaking
and mental arithmetic tasks in front of two unfamiliar ‘evaluators’.
Outcome measures: Salivary cortisol concentrations were
measured at baseline and at regular intervals after the TSST-C.
Continuous measurements of heart rate, finger blood pressure,
stroke volume, cardiac output and systemic vascular resistance
were carried out before, during and for 10 minutes after the TSSTC
using a finger cuff.
Results: Cortisol concentrations [mean increment (SD): 6.1 (6.9)
ng/mL], heart rate [4.6 (10.1) bpm], systolic [24.2 (11.6) mmHg]
and diastolic blood pressure [16.5 (7.3) mmHg], cardiac output
[0.6 (0.7) L/min], stroke volume [4.0 (5.6) mL] and systemic
vascular resistance [225 (282) dyn.s/cm5] increased significantly
(P<0.001) from baseline after inducing stress.
Conclusions: The TSST-C produces stress-responses in Indian
adolescents of a sufficient magnitude to be a useful tool for
examining stress physiology and its relationships to disease
outcomes in this population.
Description
Keywords
Cortisol, Stress, Validation studies
Citation
Krishnaveni G V, Veena S R, Jones A, Bhat D S, Malathi M P, Hellhammer D, Srinivasan K, Upadya H, Kurpad A V, Fall C H D. Trier Social Stress Test in Indian Adolescents. Indian Pediatrics. 2014 June; 51(6): 463-467.