Anti-NMDA Receptor Encephalitis in an Adolescent.
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Date
2014-05
Journal Title
Journal ISSN
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Abstract
Background: Anti N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune
mediated disorder. Case characteristics: A previously healthy 14-year-old girl presenting
with generalized tonic clonic seizures and altered behavior. Observation: In view of
refractory seizures, hallucinations, psychobehavioral and catalepsy like symptoms, and
CSF showing lymphocytic pleocytosis, possibility of autoimmune encephalitis was
considered. Serum was positive for anti-NMDA receptor antibodies. Outcome: She
recovered completely in six months without any sequelae. Conclusion: Anti-NMDA
receptor encephalitis - a potentially treatable disease - should be considered in differential
diagnosis of encephalitis when acute behavioral changes, seizures or dyskinesias are
present.
Description
Keywords
Encephalitis, Catalepsy, Psychosis, Refractory seizures
Citation
Shruthi T K, Shuba S, Rajakumar P S, Chitrambalam S. Anti-NMDA Receptor Encephalitis in an Adolescent. Indian Pediatrics. 2014 May; 51(5): 405-406.