Current Controversies in the Management of Patent Ductus Arteriosus in Preterm Infants.
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Date
2014-04
Journal Title
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Abstract
Objective: Patent ductus arteriosus is very commonly seen in very low birth weight (VLBW) infants, affecting about one-third. The
present review tries to identify the group of VLBW infants who need active intervention in day-to-day practice and to determine the mode
of intervention, based on current published literatures.
Methods: We searched the Cochrane library, MEDLINE, EMBASE and CINAHL databases, and reference that of identified trials.
Results and Conclusions: Preterm infants with a birth weight of <800g are at risk of significant morbidity and mortality from PDA; it
would be reasonable to treat them when symptomatic or if requiring positive pressure ventilator support. Those weighing >800g are
unlikely to need treatment unless they are ventilator-dependent or show evidence of congestive heart failure.
Description
Keywords
Ibuprofen, Indomethacin, Low birth-weight infants, Patent ductus arteriosus
Citation
Ibrahim Thowfique K, Haium A A Abdul, Chandran S, Rajadurai V S. Current Controversies in the Management of Patent Ductus Arteriosus in Preterm Infants. Indian Pediatrics. 2014 Apr; 51(4): 289-294.