An extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case.

Abstract
Ependymomas commonly arise in the central nervous system. Extraneural presentation is quite rare. Herein, we describe a primary extraneural ependymoma in a young female. The mass was located in the right inguinal area. The cut surface of the 7.5 mm × 6.5 mm × 4.5 mm sized tumor was brownish‑yellow in color. Histologically, it was hypercellular exhibiting pseudorosette or rosette formations and some papillary structures. Mitosis was counted as high as 10 per 10 high power fields. Neither necrosis nor vascular endothelial proliferation within the tumor was observed. Tumor cells showed strong glial fibrillary acidic protein immunoreactivity. On epithelial membrane antigen, intracytoplasmic dot‑like immunostaining was observed. This is the first report presenting a primary extraneural anaplastic ependymoma arising in the inguinal subcutaneous region.
Description
Keywords
Ependymoma, epithelial membrane antigen, extraneural tumor, glial fibrillary acidic protein, subcutaneous tumor
Citation
Sayar Hamide, Ersen Ayca, Kurtul Neslihan, Yazar Mehmet Fatih, Balakan Ozan. An extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case. Indian Journal of Pathology & Microbiology. 2015 Oct-Dec 58(4): 560-562.