Electron beam radiotherapy for the management of recurrent extensive ocular surface squamous neoplasia with orbital extension.
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Date
2015-08
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Abstract
Recurrent extensive ocular surface squamous neoplasia (OSSN)
with orbital invasion can be successfully managed with external
radiotherapy using electrons resulting in eye and vision
salvage. We report a case of right eye recurrent OSSN in an
immunocompetent adult Indian male, with extensive orbital
involvement. The patient had two previous surgical excisions
with recurrent disease. At this stage, conventionally exenteration
is considered the treatment modality. However, he was treated
with 5040 cGy radiotherapy (15eV electrons) resulting in
complete disease regression. At the end of 3 years follow‑up,
the patient was disease free, maintained a vision of 20/25, with
mild dry eye, well‑managed with topical lubricants. Extensive
OSSN with orbital invasion does not always need exenteration.
External beam electron radiotherapy provides a noninvasive
cure with organ and vision salvage and should be considered
in extensive OSSN not amenable to simple excision biopsies.
Long‑term studies to evaluate the effect of radiation on such eyes
are suggested.
Description
Keywords
Electron beam, ocular surface squamous neoplasia, radiotherapy
Citation
Murthy Ramesh, Gupta Himika, Krishnatry Rahul, Laskar Siddhartha. Electron beam radiotherapy for the management of recurrent extensive ocular surface squamous neoplasia with orbital extension. Indian Journal of Ophthalmology. 2015 Aug; 63(8): 672-674.