Mucoepidermoid carcinoma of the conjunctiva with lung metastasis.
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Date
2015-05
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Abstract
A 36‑year‑old lady presented with redness and decreased vision
in right eye since 6 months. She was earlier diagnosed of cavitary
lung lesion, presumed secondary to tuberculosis and treated
with anti‑tubercular treatment for 4 months. Examination of
affected right eye revealed nil light perception, conjunctival
congestion with an exuberant mass in the inferotemporal bulbar
conjunctiva, proptosis, iris neovascularization, 360° closed
angles, intraocular pressure of 48 mm Hg, exudative retinal
detachment, uveal mass and orbital extension. A diagnostic
needle biopsy of uveal mass revealed malignant cells. Computed
tomography‑guided lung biopsy revealed squamous cell
carcinoma (SCC), indicating metastatic spread from the orbit.
She underwent lid‑sparing exenteration of the right eye.
Histopathological examination of the orbital tissue revealed
mucoepidermoid carcinoma arising from the conjunctiva with
extensive invasion into the orbital tissue, muscle fibers, sclera,
choroid and optic nerve. Multiple tumor emboli were seen in the
lumen of orbital blood vessels. In conclusion, mucoepidermoid
carcinoma of the conjunctiva is a rare, aggressive variant of SCC.
Early intervention is essential to prevent intraocular invasion
and systemic metastasis.
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Keywords
Biopsy, conjunctiva, lung, metastasis, mucoepidermoid carcinoma, tumor
Citation
Rishi Pukhraj, Sharma Rashi, Subramanian Krishnakumar, Subramaniam Nirmala. Mucoepidermoid carcinoma of the conjunctiva with lung metastasis. Indian Journal of Ophthalmology. 2015 May; 63(5): 457-459.