Acute Lymphoblastic Leukemia with Treatment–Naïve Fanconi Anemia.
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Date
2013-05
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Abstract
Fanconi anemia is known to have a predisposition to cancer, mostly associated with acute
myeloid leukemia. We report an eight-year-old girl with treatment and naïve FA who
developed acute-lymphoblastic-leukemia (ALL). She was initiated on chemotherapy but
she failed to respond to treatment and died during induction phase of chemotherapy. While
this association may be coincidental but possibility of transition of Fanconi anemia to ALL
should be considered in view of high predisposition to cancer in this disorder.
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Keywords
Acute lymphoblastic leukemia, Aplastic anemia, Fanconi anemia, Malignancy
Citation
Shah Ankit, John Biju M, Sondhi Vishal. Acute Lymphoblastic Leukemia with Treatment–Naïve Fanconi Anemia. Indian Pediatrics. 2013 May; 50(5): 508-510.