Triglyceride and Non-High-Density Lipoprotein Cholesterol as Predictors of Cardiovascular Disease Risk Factors in Chinese Han Children.
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Date
2013-04
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Abstract
Objective: To investigate the role of serum cholesterol and
triglyceride in the assessment of cardiovascular disease risk
factors in children and adolescents.
Design: Case-control study.
Setting: Children’s Hospital of Zhejiang University School of
Medicine, Hangzhou, China.
Subjects: Children from 6 years to 17 year old. 188 with simple
obesity, and 431 with obesity and metabolic abnormalities. 274
age and gender-matched healthy children as controls.
Methods: Receiver operating characteristic curves were used to
analyze the detection of cardiovascular disease risk factors by
cholesterol and triglyceride in children and adolescents.
Results: The ranges of areas under receiver operating
characteristic curves (AUC) for triglyceride and non-high-density
lipoprotein cholesterol were 0.798-0.860 and 0.667-0.749,
respectively to detect cardiovascular disease risk factors. The
ranges of AUC for low-density lipoprotein cholesterol, total
cholesterol, and high-density lipoprotein cholesterol were 0.631-
0.718, 0.596-0.683, and 0.292-0.376, respectively.
Conclusions: Triglyceride and non-high-density lipoprotein
cholesterol are better than low-density lipoprotein cholesterol as
predictors of cardiovascular disease risk factors in Chinese Han
children and adolescents.
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Keywords
Cardiovascular disease, Children, Cholesterol, Lipids, Risk factors, Triglyceride
Citation
Zhu Wei Fen, Liang Li, Wang Chun Lin, Fu Jun Fen. Triglyceride and Non-High-Density Lipoprotein Cholesterol as Predictors of Cardiovascular Disease Risk Factors in Chinese Han Children. Indian Pediatrics. 2013 April; 50(4): 394-398.