Microwave ablation as palliative treatment of locally recurrent colorectal cancer.
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Date
2015-12
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Abstract
BACKGROUND: Patients suffering local recurrence of colorectal cancer which cannot be surgically removed are troubled with severe pain and
poor quality of life. The aim of this study is to evaluate the efficacy and safety of computed tomography (CT)‑guided microwave ablation (MWA)
as palliative treatment for recurrent unresectable colorectal cancer. MATERIALS AND METHODS: Thirty‑one patients were suffering locally recurrent
colorectal cancer underwent MWA with CT guidance. The MWA power was set at 60–80 W, 6–8 min. Effectiveness was evaluated by visual analog
scale (VAS) with a follow‑up of 6‑month. Complications were also recorded. RESULTS: Technical success was achieved in all patients. Mean VAS
preprocedure was 7.10. Mean VAS postprocedure were as follows: 1 week, 2.65 (P < 0.001); 1 month, 0.81 (P < 0.001); 3 months 0.45 (P < 0.001);
and 6 months 0.19 (P < 0.001). No serious complications were observed including intestinal fistulas, bladder fistulas, or peripheral vascular or
nerve injury. CONCLUSIONS: CT‑guided MWA as treatment of recurrent colorectal cancer can quickly and effectively relieve pain. It is a minimally
invasive, safe, and efficient palliative treatment of recurrent colorectal cancer.
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Keywords
Colorectal cancer, microwave ablation, pain
Citation
Li W, Ye X, Yang X, Li Y, Huang G, Wang J, Han X, Ni X, Wei Z, Zheng A, Meng M. Microwave ablation as palliative treatment of locally recurrent colorectal cancer. Indian Journal of Cancer. 2015 Dec; 52(6)Suppl_2: s61-s63.