Immunogenicity of Single Dose Live Attenuated Hepatitis A Vaccine.

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Date
2011-02
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Abstract
A long-term immunogenicity study of a single dose live attenuated H2 strain hepatitis A vaccine is being conducted in healthy Indian children at KEM Hospital, Pune. 131 of the original 143 children vaccinated in 2004, were evaluated for anti- HAV antibodies 30 months post vaccination (2007). Seroprotective antibody levels ≥20 mIU/mL were demonstrated in 87.8% subjects with an overall GMT of 92.02mIU/mL. No hepatitis like illness was recorded in any of the subjects since vaccination
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Keywords
Hepatitis A, Immunogenicity, India, Live attenuated vaccine, Seroprotection
Citation
Bhave Sheila, Bavdekar Ashish, Sapru Amita, Bawangade Seema, Pandit Anand. Immunogenicity of Single Dose Live Attenuated Hepatitis A Vaccine. Indian Pediatrics. 2011 Feb; 48(2): 135-137.