Portal Hypertension with Visceral Leishmaniasis.
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Date
2010-11
Journal Title
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Abstract
We conducted this study to observe evidence of portal hypertension in children
with visceral leishmaniasis (VL). Eighty-eight consecutive cases (50 male) of VL
were subjected to ultrasonography. Those with evidence of portal hypertension
also underwent upper gastrointestinal endoscopy and liver biopsy. Eight patients
had portal hypertension as evidenced by dilated caliber of portal and splenic veins.
Two patients had periportal, splenic and peripancreatic collaterals and one patient
had cavernous transformation of portal vein. Out of eight patients, four patients had
esophageal and gastric varices. Liver biopsy was done in four patients and
revealed hepatic sinusoidal dilations without any evidence of fibrosis. Portal
hypertension may be an independent manifestation of VL and remain
undiagnosed unless a physician maintains a high index of suspicion.
Description
Keywords
India, Kala-azar, Portal hypertension, ltrasonography, Visceral leishmaniasis
Citation
Prasad Rajniti, Singh Utpal Kant, Mishra O P, Jaiswal BP, Muthusami Sunil. Portal Hypertension with Visceral Leishmaniasis. Indian Pediatrics. 2010 Nov; 47(11): 965-967.