Tolerance of Baby Cleansers in Infants: A Randomized Controlled Trial.
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Date
2010-11
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Abstract
This randomized controlled trial was conducted to evaluate the tolerability of a new
baby cleanser formulation - Johnson’s Top-to-Toe cleanser (JTT) on infantile skin.
180 healthy infants (60 in each group) were enrolled and JTT Sebamed Baby
Liquid cleanser (SM), and lukewarm tap water were used on the skin of the
subjects as whole body cleansers twice a week for 2 weeks. Assessment was done
at baseline, 1 week and 2 weeks clinically by a dermato-logist, instrumentally, and
by the parents. Clinical assessment (erythema, edema, dryness and scaling); skin
moisture content; skin surface pH; trans-epidermal water loss; skin oxyhemoglobin
and deoxyhemoglobin; and consu-mer satisfaction were the outcome measures.
There was no significant erythema, edema, dryness, or scaling elicited by any of the
three test components. Parents did not report any side-effects. All the three studied
interventions used as whole body cleansers were efficacious and well tolerated by
infants.
Description
Keywords
Baby cleanser, Infant, Moisture, Tolerability, Epidermal water loss, Skin.
Citation
Dizon Ma Victoria, Galzote Carlos, Estanislao Ricco, Mathew Noble, Sarkar Rashmi. Tolerance of Baby Cleansers in Infants: A Randomized Controlled Trial. Indian Pediatrics. 2010 Nov; 47(11): 959-963.