Effects of Enteral Insulin on Hypoxic Changes in a Rat Model of Necrotizing Enterocolitis.

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Date
2010-10
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Abstract
The aim of this study was to determine if oral administration of insulin would protect intestinal cell damage in a hypoxia-induced experimental NEC model in rats. Rats were subjected to hypoxia-reoxygenation and then were returned to standard conditions, other were treated with insulin. According to our results, oral insulin does not prevent mild intestinal mucosal changes during hypoxic injury in rats.
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Keywords
Hypoxia, Insulin, Necrotizing enterocolitis
Citation
Yurdakok Begum, Canpolat Fuat Emre, Orhan Diclehan, Kale Gulsev. Effects of Enteral Insulin on Hypoxic Changes in a Rat Model of Necrotizing Enterocolitis. Indian Pediatrics. 2010 Oct; 47(10): 887-888.