A Green Protocol for the Synthesis and Antimicrobial Evaluation of Some Imidazo [1,2-A] Pyrazines.

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Date
2015-04
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Abstract
In this work, we have described a simple and convenient method for the synthesis Imidazo [1,2-a] pyrazine derivatives using 2-amino5-bromo pyrazine, and phenacyl bromide in the presence of DABCO as a catalyst and evaluated as antimicrobial agents. The notable features of this protocol are the simple experimental procedure, short reaction time, easy handling and good yields using a catalytic amount of readily available and cost effective catalyst.
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Keywords
2-amino 5- bromopyrazine, Antimicrobial activity DABCO, Green Chemistry, Imidazo [1,2-a] pyrazine
Citation
Pandya Jalpa R, Goswami Vaishali M, Joshi Hitendra S. A Green Protocol for the Synthesis and Antimicrobial Evaluation of Some Imidazo [1,2-A] Pyrazines. International Journal of Applied Biology and Pharmaceutical Technology. 2015 Apr-June; 6(2): 108-112.