A Study of Serum Zinc level in Cirrhosis of Liver.
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Date
2012
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Abstract
Cirrhosis is a consequence of chronic liver diseases. Zinc is a micronutrient that plays an
important role in the function of liver. This cross-sectional study was carried out in the
Department of Biochemistry, Dhaka Medical College, from July 2010 to June 2011 to
observe the association of serum zinc level with liver cirrhosis. A total of 100 adults, both
males and females with age range of 18-60 years, of which 50 were healthy subjects and 50
adult hospitalised cirrhotic patients were selected purposively for the study according to
selection crieteria. Fasting serum zinc level was measured with atomic absorption
spectrophotometer. Serum zinc level was found to be low in 72% patients. Mean ±SD of
serum zinc levels (μg/L) were 610.32 ± 169.60 and 827.66 ± 267.32 in cases and controls
respectively. In cirrhotic patients serum zinc level was significantly lower than that of
healthy controls (P<0.001). Though, it is difficult to draw any definite conclusion from this
study, because of reduced level serum of zinc found in cirrhotics, Zn may be supplemented
to them with a hope of better treatment response.
Description
Keywords
Liver Cirrhosis, Zinc
Citation
Atia F, sultana N, Ahmed S, Ferdousi S, sultana R, Atiquzzaman M. A Study of Serum Zinc level in Cirrhosis of Liver. Bangladesh Journal of Medical Biochemistry. 2012; 5(2): 44-47.