Association of Serum Calcium and 24 Hours Urinary Excretion of Calcium in Patients of Preeclampsia.
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Date
2010
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Abstract
Preeclampsia is a leading cause of fetal growth retardation, infant morbidity, mortality and
maternal death. Several biochemical changes occur during the course of the disease,
among them serum total calcium and 24 hr urinary calcium excretion rate have drawn
remarkable attention. A case control study was designed to see the association of serum
calcium and 24 hours urinary excretion of calcium in patients of pre- eclampsia. The
study was done from July 2008 to June 2009 in the Department of Biochemistry, Dhaka
Medical College, Dhaka. Total 60 subjects were selected as study population. Among
them 30 were diagnosed case of preeclampsia and 30 were age- and sex-matched
normal pregnant female healthy control. It was found that the mean measured serum
calcium level in case group were 1.96 ±0.17 ( mean±SD ) mmol / l and that of
control group were 2.34±0.12 (mean±SD) m mol/ l respectively. The mean 24 hr
urinary calcium excretion level were 94.40 ±10.68mg/24 hr (mean±SD) in case group
and that of control group were 154.35±66.68 (mean ±SD) mg / 24 hr respectively. The
study suggests that low level of serum calcium and urinary excretion of calcium was
associated with Pre-eclampsia.
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Keywords
Pre-eclampsia, Serum calcium, 24 hr urinary calcium
Citation
Khatun, Kirtania K, Shima T S, Ferdous S, Shahnaz A, Yeasmin F, Sultana N. Association of Serum Calcium and 24 Hours Urinary Excretion of Calcium in Patients of Preeclampsia. Bangladesh Journal of Medical Biochemistry. 2010; 3(2): 57-60.